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dc.rights.licenseAttribution 4.0 International*
dc.contributor.authorZabala, Alaitz
dc.contributor.authorLlavori, Inigo
dc.contributor.authorLarrañaga Altuna, Mikel
dc.contributor.otherPearce, Oliver
dc.contributor.otherNguyen, Dinh T
dc.contributor.otherCaro, Jaume
dc.contributor.otherMescheder, Holger
dc.contributor.otherEndrino, Jose L.
dc.contributor.otherGoela, Gaurav
dc.contributor.otherAyre, Wayne Nishio
dc.contributor.otherSeenivasagam, Rajkumar Kottayasamy
dc.contributor.otherTripathy, Debendra Kumar
dc.contributor.otherGoel, Saurav
dc.date.accessioned2021-04-29T06:55:47Z
dc.date.available2021-04-29T06:55:47Z
dc.date.issued2021
dc.identifier.issn1931-9401en
dc.identifier.otherhttps://katalogoa.mondragon.edu/janium-bin/janium_login_opac.pl?find&ficha_no=162937en
dc.identifier.urihttps://hdl.handle.net/20.500.11984/5282
dc.description.abstractProgress made by materials scientists in recent years has greatly helped the field of ultra-precision manufacturing. Ranging from healthcare to electronics components, phenomena such as twinning, dislocation nucleation, and high-pressure phase transformation have helped to exploit plasticity across a wide range of metallic and semiconductor materials. One current problem at the forefront of the healthcare sector that can benefit from these advances is that of bacterial infections in implanted prosthetic devices. The treatment of implant infections is often complicated by the growth of bacterial biofilms on implant surfaces, which form a barrier that effectively protects the infecting organisms from host immune defenses and exogenous antibiotics. Further surgery is usually required to disrupt the biofilm, or to remove the implant altogether to permit antibiotics to clear the infection, incurring considerable cost and healthcare burdens. In this review, we focus on elucidating aspects of bactericidal surfaces inspired by the biological world to inform the design of implant surface treatments that will suppress bacterial colonization. Alongside manufacturing and materials related challenges, the review identifies the most promising natural bactericidal surfaces and provides representative models of their structure, highlighting the importance of the critical slope presented by these surfaces. The scalable production of these complex hierarchical structures on freeform metallic implant surfaces has remained a scientific challenge to date and, as identified by this review, is one of the many 21st-century puzzles to be addressed by the field of applied physics.en
dc.description.sponsorshipUnión Europeaes
dc.description.sponsorshipinfo:eu-repo/grantAgreement/EC/H2020/665337/EU/Laser-induced Nanostructures as Biomimetic Model of Fluid Transport in the Integument of Animals/LiNaBioFluides
dc.description.sponsorshipDiputación Foral de Gipuzkoaes
dc.language.isoengen
dc.publisherAIP Publishingen
dc.rights© 2021 Author(s)en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleBactericidal Surfaces: An Emerging 21st Century Ultra-Precision Manufacturing and Materials Puzzleen
dcterms.accessRightshttp://purl.org/coar/access_right/c_abf2en
dcterms.sourceApplied Physics Reviewsen
local.contributor.groupTecnologías de superficieses
local.description.peerreviewedtrueen
local.identifier.doihttps://doi.org/10.1063/5.0028844en
local.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/814494/EU/Intelligent Open Test Bed for Materials Tribological Characterisation Services/i-TRIBOMATen
local.relation.projectIDDFG/Programa de Red guipuzcoana de Ciencia, Tecnología e Innovación 2018/OF-118-2018/GIP/Investigación y análisis de estrategias para incrementar la eficiencia energética del ascensor/ASEFIen
local.rights.publicationfeeAPCen
local.contributor.otherinstitutionhttps://ror.org/05cncd958es
local.contributor.otherinstitutionhttps://ror.org/05jt1df44es
local.contributor.otherinstitutionEurecat Centre Tecnològic de Catalunyaes
local.contributor.otherinstitutionhttps://ror.org/00t0rcy29es
local.contributor.otherinstitutionUPV/EHUes
local.contributor.otherinstitutionhttps://ror.org/01cc3fy72es
local.contributor.otherinstitutionhttps://ror.org/02vwnat91es
local.contributor.otherinstitutionhttps://ror.org/03kk7td41es
local.contributor.otherinstitutionhttps://ror.org/02dwcqs71es
local.contributor.otherinstitutionhttps://ror.org/05aqahr97es
local.source.detailsVol. 8. N. artículo 021303, 2021en
oaire.format.mimetypeapplication/pdf
oaire.file$DSPACE\assetstore
oaire.resourceTypehttp://purl.org/coar/resource_type/c_6501en
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85en


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