Listar por autor "Gómez Esteban, Juan Carlos"
Mostrando ítems 1-7 de 7
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Association of retinal neurodegeneration with the progression of cognitive decline in Parkinson’s disease
Romero-Bascones, David; Ayala, Unai; Barrenechea, Maitane (Springer Nature, 2024)Retinal thickness may serve as a biomarker in Parkinson’s disease (PD). In this prospective longitudinal study, we aimed to determine if PD patients present accelerated thinning rate in the parafoveal ganglion cell-inner ... -
Clinical long-term nocturnal sleeping disturbances and excessive daytime sleepiness in Parkinson's disease
Ayala, Unai (PLOS, 2021)Objective To prospectively evaluate nocturnal sleep problems and excessive daytime sleepiness (EDS) in Parkinson’s disease (PD) patients, and analyze the influence of motor symptoms, treatment, and sex differences on sleep ... -
Foveal Pit Morphology Characterization: A Quantitative Analysis of the Key Methodological Steps
Romero-Bascones, David; Barrenechea, Maitane; Ayala, Unai (MDPI, 2021)Disentangling the cellular anatomy that gives rise to human visual perception is one of the main challenges of ophthalmology. Of particular interest is the foveal pit, a concave depression located at the center of the ... -
Foveal Remodeling of Retinal Microvasculature in Parkinson’s Disease
Barrenechea, Maitane; Erramuzpe Aliaga, Asier; Ayala, Unai; Romero-Bascones, David (Frontiers, 2021)Background: Retinal microvascular alterations have been previously described in Parkinson’s disease (PD) patients using optical coherence tomography angiography (OCT-A). However, an extensive description of retinal vascular ... -
Heart-brain synchronization breakdown in Parkinson’s disease
Erramuzpe Aliaga, Asier (Springer Nature, 2022)Heart rate variability (HRV) abnormalities are potential early biomarkers in Parkinson’s disease (PD) but their relationship with central autonomic network (CAN) activity is not fully understood. We analyzed the synchronization ... -
Retinal thickness as a biomarker of cognitive impairment in manifest Huntington’s disease
Romero-Bascones, David; Ayala, Unai (Springer Nature, 2023)Background Cognitive decline has been reported in premanifest and manifest Huntington’s disease but reliable biomarkers are lacking. Inner retinal layer thickness seems to be a good biomarker of cognition in other ... -
Spatial characterization of the effect of age and sex on macular layer thicknesses and foveal pit morphology
Romero-Bascones, David; Ayala, Unai; Alberdi Aramendi, Ane; Erramuzpe Aliaga, Asier; Barrenechea, Maitane (PLoS, 2022)Characterizing the effect of age and sex on macular retinal layer thicknesses and foveal pit morphology is crucial to differentiating between natural and disease-related changes. We applied advanced image analysis techniques ...
