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dc.rights.licenseAttribution-NonCommercial 4.0 International*
dc.contributor.authorSoto-Gordoa, Myriam
dc.contributor.otherMar, Javier
dc.contributor.otherZubiagirre, Uxue
dc.contributor.otherLarrañaga, Igor
dc.contributor.otherMar Barrutia, Lorea
dc.contributor.otherGonzález, Ana
dc.contributor.otherIbarrondo Olagüenaga, Oliver
dc.date.accessioned2024-10-23T14:49:06Z
dc.date.available2024-10-23T14:49:06Z
dc.date.issued2024
dc.identifier.issn1387-2877en
dc.identifier.otherhttps://katalogoa.mondragon.edu/janium-bin/janium_login_opac.pl?find&ficha_no=178008en
dc.identifier.urihttps://hdl.handle.net/20.500.11984/6680
dc.description.abstractBackground: Antipsychotics are widely used in the elderly due to the high prevalence of neuropsychiatric associated with dementia. Objective: To analyze potential disparities in antipsychotic use in the general population of Gipuzkoa by socioeconomic status (SES) and diagnosis of Alzheimer’s disease and related dementia (ADRD) adjusting for somatic and psychiatric comorbidities, age, and sex. Methods: A retrospective observational study was carried out in all the 221,777 individuals over 60 years of age (Gipuzkoa, Spain) to collect diagnosis of ADRD, the Charlson Comorbidity Index, and psychiatric comorbidities considering all primary, outpatient, emergency and inpatient care episodes and first- and second-generation antipsychotics, and sociodemographic variables, namely, age, sex, SES and living in a nursing home. Logistic regression was used for multivariate statisticalanalysis. Results: Use of any antipsychotic was greater in women, individuals over 80 years old, living in a nursing home, with a diagnosis of dementia, somatic and psychiatric comorbidities, and low SES. Quetiapine was the most used drug. The likelihood of any antipsychotic use was significantly associated with low SES (odds ratio [OR]: 1.60; confidence interval [CI]: 1.52–1.68), age over 80 years (OR: 1.56; CI: 1.47–1.65), institutionalization (OR: 12.61; CI: 11.64–13.65), diagnosis of dementia (OR: 10.18; CI: 9.55–10.85) and the comorbidities of depression (OR: 3.79; CI: 3.58–4.01) and psychosis (OR: 4.96; CI: 4.64–5.30). Conclusions: The greater levels of antipsychotic use and institutionalization in people of low SES indicate inequity in the management of neuropsychiatric symptoms. Increasing the offer of non-pharmacological treatments in the health system might help reduce inequity.en
dc.language.isoengen
dc.publisherIOS Pressen
dc.rights© 2024 The Authorsen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectAlzheimer’s diseaseen
dc.subjectantipsychotics agentsen
dc.subjectComorbidityen
dc.subjectdementiaen
dc.subjectdisparitiesen
dc.subjectnursing homeen
dc.subjectquetiapine fumarateen
dc.subjectSocial inequalityen
dc.subjectODS 3 Salud y bienestares
dc.titleDisparities by socioeconomic status and diagnosis of dementia in the prescribing of antipsychotics in a real-World data population over 60 years of ageen
dcterms.accessRightshttp://purl.org/coar/access_right/c_abf2en
dcterms.sourceJournal of Alzheimer's Diseaseen
local.contributor.groupDirección de operaciones logístico productivases
local.description.peerreviewedtrueen
local.description.publicationfirstpage645en
local.description.publicationlastpage655en
local.identifier.doihttps://doi.org/10.3233/JAD-240004en
local.contributor.otherinstitutionhttps://ror.org/02g7qcb42en
local.contributor.otherinstitutionhttps://ror.org/03ths8210en
oaire.format.mimetypeapplication/pdfen
oaire.file$DSPACE\assetstoreen
oaire.resourceTypehttp://purl.org/coar/resource_type/c_6501en
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85en
dc.unesco.tesaurohttp://vocabularies.unesco.org/thesaurus/concept10264en
dc.unesco.tesaurohttp://vocabularies.unesco.org/thesaurus/concept8189en
dc.unesco.clasificacionhttp://skos.um.es/unesco6/3202en
dc.unesco.clasificacionhttp://skos.um.es/unesco6/3212en


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Registro sencillo

Attribution-NonCommercial 4.0 International
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