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dc.contributor.authorZubia-Aranburu, Judith
dc.contributor.authorBuruaga, Lorea
dc.contributor.authorZabala, Alaitz
dc.contributor.otherMartin-Inaraja, Myriam
dc.contributor.otherRodriguez, Clara
dc.contributor.otherSantos, Silvia
dc.contributor.otherSilván, Unai
dc.contributor.otherEguizabal, Cristina
dc.date.accessioned2024-03-25T10:16:24Z
dc.date.available2024-03-25T10:16:24Z
dc.date.issued2024
dc.identifier.issn2050-6260en
dc.identifier.otherhttps://katalogoa.mondragon.edu/janium-bin/janium_login_opac.pl?find&ficha_no=174294en
dc.identifier.urihttps://hdl.handle.net/20.500.11984/6307
dc.description.abstractSince electrospinning can generate micro- to nanometre-scale fibres, it is widely used for fabricating wound dressings. Electrospun scaffolds with defined three-dimensional patterns at the mat surface can be efficiently fabricated using textured collectors that transfer the topography during the manufacturing process. However, the efficacy of surface pattern transfer from the collector to the mat, the correlation between the topography and the absorption capability and the effect of sterilisation on absorption have not yet been analysed. In this study, textured patterns were imprinted over polycaprolactone electrospun mats using textured collectors. The successful transferability of the patterns was quantified through height, hybrid and functional surface topography parameters. Additionally, ethylene oxide, hydrogen peroxide (H2O2) and ultraviolet (UV) sterilisation methods were tested, of which only UV preserved the morphological and functional integrity of the mat. Finally, fibroblasts were used to analyse the cytotoxicity and cellular response of the dressings, verifying their biocompatible nature. This study demonstrates that absorption capacity can be modulated by the surface texture of the wound dressing. The S dq and S dr parameters were identified as key surface characteristics for enhancing absorption capacity and yielded an increase of up to 176.76% compared with the non-textured control, thus revealing the potential of surface functionalisation for increasing exudate absorption.en
dc.language.isoengen
dc.publisherEmeralden
dc.rights© 2023 Emeralden
dc.subjectAbsorptionen
dc.subjectcharacterisationen
dc.subjectelectrospinningen
dc.subjectPCL (polycaprolactone)en
dc.subjectSterilisationen
dc.subjectsurface modificationen
dc.subjectsurface roughnessen
dc.subjectsurface textureen
dc.titleTowards tailored surface topography on electrospun wound dressings for exudate absorptionen
dcterms.accessRightshttp://purl.org/coar/access_right/c_abf2en
dcterms.sourceSurface Innovationsen
local.contributor.groupTecnologías de superficieses
local.description.peerreviewedtrueen
local.identifier.doihttps://doi.org/10.1680/JSUIN.23.00044en
local.contributor.otherinstitutionhttps://ror.org/0061s4v88en
local.source.detailsVol. 12. N. 3-4. N. art. 2300044, 2024
oaire.format.mimetypeapplication/pdfen
oaire.file$DSPACE\assetstoreen
oaire.resourceTypehttp://purl.org/coar/resource_type/c_6501en
oaire.versionhttp://purl.org/coar/version/c_ab4af688f83e57aaen
oaire.funderNameGobierno Vascoen
oaire.funderNameGobierno Vascoen
oaire.funderNameGobierno Vascoen
oaire.funderIdentifierhttps://ror.org/00pz2fp31 / http://data.crossref.org/fundingdata/funder/10.13039/501100003086en
oaire.funderIdentifierhttps://ror.org/00pz2fp31 / http://data.crossref.org/fundingdata/funder/10.13039/501100003086
oaire.funderIdentifierhttps://ror.org/00pz2fp31 / http://data.crossref.org/fundingdata/funder/10.13039/501100003086
oaire.fundingStreamAyudas a proyectos de investigación y desarrollo en salud 2020en
oaire.fundingStreamAyudas a proyectos de investigación y desarrollo en salud 2021en
oaire.fundingStreamAyudas a proyectos de investigación y desarrollo en salud 2022en
oaire.awardNumber2020333032en
oaire.awardNumber2021333057en
oaire.awardNumber2022333044en
oaire.awardTitleEstandarización en la obtención y preservación de plasma rico en plaquetas alogénico, creación de apósitos 3D biodegradables y biocompatibles con factores plaquetares para la curación de heridas crónicas (ALOPRP3D)en
oaire.awardTitleCreación de apósitos con plasma rico en plaquetas alogénicos para la curación de heridas crónicas (ALOPRP3D II)en
oaire.awardTitleCreación de apósitos con plasma rico en plaquetas alogénicos para la curación de heridas crónicas (ALOPRP3D III)en
dc.unesco.campohttp://skos.um.es/unesco6/33en
dc.unesco.disciplinahttp://skos.um.es/unesco6/3313en


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