2026-04-10T12:35:57Zhttps://ebiltegia.mondragon.edu/oai/request

oai:ebiltegia.mondragon.edu:20.500.11984/69982025-05-14T06:15:29Zcom_20.500.11984_473col_20.500.11984_478

Sánchez Sánchez, Ana Asenjo Sanz, Isabel Buruaga, Lorea Pomposo, José A. 2025-05-13T15:41:15Z 2025-05-13T15:41:15Z 2012 1521-3927 https://katalogoa.mondragon.edu/janium-bin/janium_login_opac.pl?find&ficha_no=128551 https://hdl.handle.net/20.500.11984/6998 Protection of acetylenic monomers is a common practice to avoid parasitic side reactions during polymerization. Herein, we report that redox-initiated RAFT polymerization allows the direct, room temperature synthesis of a variety of single-chain nanoparticle precursors (displaying narrow molecular weight dispersity, equation image/equation image = 1.12 –1.37 up to equation image = 100 kDa) containing well-defined amounts of naked, unprotected acetylenic functional groups available for rapid and quantitative intrachain cross-linking via metal-catalyzed carbon–carbon coupling (i.e., C–C “click” chemistry). To illustrate the useful “self-clickable” character of the new unprotected acetylenic precursors, single-chain nanoparticles have been prepared for the first time in a facile and highly efficient manner by copper-catalyzed alkyne homocoupling (i.e., Glaser–Hay coupling) at room temperature under normal air atmosphere. eng © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Nanotechnology Naked and Self-Clickable Propargylic-Decorated Single-Chain Nanoparticle Precursors via Redox-Initiated RAFT Polymerization http://purl.org/coar/resource_type/c_6501