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dc.contributor.authorMartin-Mayor, Alain
dc.contributor.authorBou-Ali, M. Mounir
dc.contributor.authorAginagalde, Maialen
dc.contributor.authorUrteaga, Pedro
dc.date.accessioned2022-07-05T14:35:55Z
dc.date.available2022-07-05T14:35:55Z
dc.date.issued2018
dc.identifier.issn1778-4166en
dc.identifier.otherhttps://katalogoa.mondragon.edu/janium-bin/janium_login_opac.pl?find&ficha_no=128391en
dc.identifier.urihttps://hdl.handle.net/20.500.11984/5625
dc.description.abstractThe numerical and experimental results presented in this work show that a relatively small temperature gradient (5K), has great potential to generate a separation in interesting mixtures for biological purpose. In fact, it improves molecular diffusion separation process of a protective cryo (10% of dimethyl sulfoxide (DMSO) in phosphate buffered saline (PBS)) for cryopreserved cells, by 10%. This separation process was analyzed both numerically and experimentally, for which it was necessary to determine experimentally the thermophysical and transport properties of the mixture of 10% of DMSO in PBS. Experimental tests were done in a microdevice with a working section of 500μ m × 25 mm and a length of 75 mm, which was designed, constructed and first of all validated with the mixture of reference H2O-Isopropanol at a mass fraction of 50%. Experimental test with the protective cryo were done with in flow rates between 1000μL/min and 4000μL/min. The results confirm that the effect of thermodiffusion must be considered in handling processes of biological fluid mixtures because the existence of a thermal gradient could improve the efficiency of the separation process in microdevices.es
dc.description.sponsorshipGobierno de Españaes
dc.description.sponsorshipGobierno Vascoes
dc.language.isoengen
dc.publisherElsevier B.V.en
dc.rights© 2017 Elsevier Masson SAS. All rights reserved.en
dc.subjectMicrofluidicses
dc.subjectTransport propertieses
dc.subjectThermodiffusiones
dc.subjectBiotechnologyes
dc.titleMicrofluidic separation processes using the thermodiffusion effectes
dcterms.accessRightshttp://purl.org/coar/access_right/c_abf2en
dcterms.sourceInternational Journal of Thermal Sciencesen
local.contributor.groupMecánica de fluidoses
local.description.peerreviewedtrueen
local.description.publicationfirstpage279en
local.description.publicationlastpage287en
local.identifier.doihttps://doi.org/10.1016/j.ijthermalsci.2017.10.024en
local.relation.projectIDinfo:eu-repo/grantAgreement/GE/Proyectos de I+D de Excelencia 2014/FIS2014-58950-C2-1-P/ES/Determinación de los coeficientes de difusión molecular, termodifusión y Soret en mezclas ternarias/TERDISOMEZen
local.relation.projectIDinfo:eu-repo/grantAgreement/GV/Proyectos de Investigación Básica y Aplicada 2014-2016/ PC2014-03/CAPV/Desarrollo de una nueva tecnología a escala micro para la separación y recogida de diferentes poblaciones de exosoma/MICROXOMen
local.relation.projectIDinfo:eu-repo/grantAgreement/GV/Elkartek 2016/KK-2016-00030/CAPV/Microtecnologías como motor de desarrollo de sistemas ciber-físicos avanzados involucrados en la fábrica inteligente/MICRO4FABen
local.relation.projectIDinfo:eu-repo/grantAgreement/GV/Ikertalde Convocatoria 2016-2021/IT1009-16/CAPV/Mecánica de fluidos/en
local.source.detailsVol. 124. Pp. 279-287. February, 2018en
oaire.format.mimetypeapplication/pdf
oaire.file$DSPACE\assetstore
oaire.resourceTypehttp://purl.org/coar/resource_type/c_6501en
oaire.versionhttp://purl.org/coar/version/c_ab4af688f83e57aaen


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