Listar por autor "79a7e6b178359d9e519c1e002ede7f1e"
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11-β Hydroxysteroid dehydrogenase type 2 expression in white adipose tissue is strongly correlated with adiposity
Milagro, Fermin I.; Campion, Javier; Martínez, José A. (Elsevier, 2007)Glucocorticoid action within the cells is regulated by the levels of glucocorticoid receptor (GR) expression and two enzymes, 11-β hydroxysteroid dehydrogenase type 1 (11βHSD1), which converts inactive to active glucocorticoids, ... -
Adiposity dependent apelin gene expression: relationships with oxidative and inflammation markers
Garcia-Diaz, Diego; Campion, Javier; Milagro, Fermin I.; Martínez, José A. (Springer Nature Link, 2007)It has been reported that apelin functions as an adipokine, which has been associated to obesity and insulin resistance. The objective of this study was to analyze the apelin mRNA expression in white adipose tissue ... -
Diferential gene expression and adiposity reduction induced by ascorbic acid supplementation in a cafeteria model of obesity
Campion, Javier; Milagro, Fermin I.; Fernández, D.; Martínez, J.A, (Springer Nature Link, 2006)Obesity is considered as an inflammatory disease, in which free radical-induced oxidative stress and excessive intake of macronutrients exacerbate their symptoms. In this context, we assessed in rats the possible preventive ... -
Vitamin C Supplementation Influences Body Fat Mass and Steroidogenesis-Related Genes when Fed a High-Fat Diet
Campion, Javier; Milagro, Fermin I.; Fernandez Orth, Dietmar; Martínez, J. Alfredo (Hogrefe AG, 2008)An enhanced oxidative stress status has been documented in obese patients and animal models, and a depletion of the antioxidant mechanisms in these conditions is a common feature. Therefore, we have tested the hypothesis ... -
Weight gain induced by high-fat feeding involves increased liver oxidative stress
Milagro, Fermin I.; Campion, Javier; Martínez, José A. (John Wiley & Sons, Ltd, 2012)Objective: To assess the effects of high-fat feeding on white adipose tissue gene expression and liver oxidative stress.Research Methods and Procedures: Male Wistar rats were fed on standard pelleted or high-fat diet to ...
